A NUMERICAL STUDY OF THE SHAPE OF THE SURFACE SEPARATING FLOW INTO BRANCHES IN MICROVASCULAR BIFURCATIONS

A NUMERICAL STUDY OF THE SHAPE OF THE SURFACE SEPARATING FLOW INTO BRANCHES IN MICROVASCULAR BIFURCATIONS
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DOI:
10.1115/1.2891401
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发表时间:
1992-08-01
影响因子:
1.7
通讯作者:
POPEL, AS
POPEL, AS
中科院分区:
工程技术4区
文献类型:
--
作者:
ENDEN, G;POPEL, AS

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由进入微血管分叉分支的流线形成的分离面的形状在决定分叉下游的红细胞和其他血液成分的分布方面起着重要作用。采用有限元方法,通过数值求解三维N-S方程,确定了圆管T型分叉内低雷诺数流体流动的表面形状。计算了大范围的子血管与母体血管的直径比和流量比。此外,还研究了雷诺数的影响。我们的数值结果与Rong和Carr(《微血管研究》,第39卷,第186-202页,1990)的实验数据吻合得很好。这项研究的数值结果将用于预测微血管分支下游血液成分的浓度,前提是入口浓度分布已知。
The shape of the separating surface formed by the streamlines entering the branches of microvascular bifurcations plays a major role in determining the distribution of red blood cells and other blood constituents downstream from the bifurcation. Using the finite element method, we determined the shape of the surface through numerical solution of three dimensional Navier-Stokes equations for fluid flow at low Reynolds numbers in a T-type bifurcation of circular tubes. Calculations were done for a wide range of daughter branch to parent vessel diameter ratios and flow ratios. The effect of Reynolds number was also studied. Our numerical results are in good agreement with previously reported experimental data of Rong and Carr (Microvascular Research, Vol. 39, pp. 186-202, 1990). The numerical results of this study will be used to predict the concentration of blood constituents downstream from microvascular bifurcations providing that the inlet concentration profile is known.