Osseointegration aspects of placed implant in bone reconstruction with newly developed block-type interconnected porous calcium hydroxyapatite.
Osseointegration aspects of placed implant in bone reconstruction with newly developed block-type interconnected porous calcium hydroxyapatite.
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DOI：
10.1590/1678-775720150597
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发表时间：
2016-07
期刊：
影响因子：
--
通讯作者：
Tsuga K
中科院分区：
文献类型：
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作者：
Doi K;Kubo T;Makihara Y;Oue H;Morita K;Oki Y;Kajihara S;Tsuga K
人工骨已被用于骨缺损的修复。然而，关于块骨移植后种植体放置的报道很少。本研究的目的是评价多孔羟基磷灰石钙（IP-CHA）骨重建中种植体的骨整合性。将IP-CHA柱（D; 4.3 mm， H; 10.0 mm）分别置入4只公犬股骨两侧的骨臼内。右侧的IP-CHA是24周的样本。放置12周后，将钛植入物放置在右侧放置的IP-CHA圆柱体的一半处准备好的套孔中。左侧放置另一个IP-CHA圆柱体作为12周样本。再过12周，采集标本，测量骨再生和骨-种植体接触率（BIC）。新骨形成面积在24周IP-CHA组优于12周IP-CHA组。IP-CHA与母站点间的BIC差异不显著。在ip - cha重建骨中，种植体周围可见骨整合。我们的初步结果表明IP-CHA可能是一种合适的骨移植材料，用于重建需要植入的骨。
Artificial bone has been employed to reconstruct bone defects. However, only few reports on implant placement after block bone grafting exist. The purpose of this study was to evaluate the osseointegration of dental implant in bone reconstructions with interconnected porous calcium hydroxyapatite (IP-CHA). The IP-CHA cylinders (D; 4.3 mm, H; 10.0 mm) were placed into bone sockets in each side of the femurs of four male dogs. The IP-CHA on the right side was a 24-week sample. Twelve weeks after placement, a titanium implant was placed into a socket that was prepared in half of the placed IP-CHA cylinder on the right side. On the left side, another IP-CHA cylinder was placed as a 12-week sample. After another 12 weeks, the samples were harvested, and the bone regeneration and bone-implant contact (BIC) ratios were measured. New bone formation area was superior in the 24-week IP-CHA compared with the 12-week IP-CHA. BIC was not significantly different between IP-CHA and the parent sites. Osseointegration was detected around the implant in IP-CHA-reconstructed bone. Our preliminary results suggest that IP-CHA may be a suitable bone graft material for reconstructing bones that require implant placement.