Evaluation of left ventricular strain in patients with dilated cardiomyopathy
Evaluation of left ventricular strain in patients with dilated cardiomyopathy
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DOI：
10.1177/0300060517712164
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Lianggeng Gong
中科院分区：
文献类型：
--
作者：
Yaohan Yu;Sisi Yu;Xuepei Tang;Haibo Ren;Shuhao Li;Qian Zou;Fakui Xiong;Tian Zheng;Lianggeng Gong
Objective: Dilated cardiomyopathy (DCM) can cause structural and functional changes in the left ventricle (LV). In this study, we evaluated whether cardiac magnetic resonance tissue-tracking (MR-TT) can be applied to the detection of LV abnormalities in patients with DCM. Methods: We used MR-TT to analyze the global peak radial strain (GPRS), global peak circumferential strain (GPCS), and global peak longitudinal strain (GPLS) in every segment of the LV in 23 patients with DCM and 25 controls. The LVejection fraction was also measured as a function indicator. Results: Compared with the controls, the GPRS, GPCS, and GPLS were significantly reduced in patients with DCM, indicating global LV function impairment in all directions. We also identified a significant linear correlation between the GPRS, GPCS, and GPLS and the LV ejection fraction, indicating that LV function relies on coordinated wall motion from all directions. Moreover, we found that patients with DCM had a significantly reduced magnitude of the PRS, PCS, and PLS in most segments at different levels, indicating impaired myocardial function in most LV regions. Conclusions: Our results demonstrate that LV myocardial strain in patients with DCM can be sensitively detected by MR-TT (not only the global LV function changes but also the segmental strain), which can help to identify the injured segment at an early stage and guide clinical treatment.
