Contribution of the right intraparietal sulcus to numerosity and length processing: An fMRI-guided TMS study
Contribution of the right intraparietal sulcus to numerosity and length processing: An fMRI-guided TMS study
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DOI：
10.1016/j.cortex.2011.05.019
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发表时间：
2012-05-01
期刊：
影响因子：
3.6
通讯作者：
Pesenti, Mauro
中科院分区：
文献类型：
--
作者：
Dormal, Valerie;Andres, Michael;Pesenti, Mauro
利用神经导航重复经颅磁刺激（rTMS）测试了左右顶内沟（IPS）在数字和长度处理中的关键参与。参与者必须将点的线性阵列分类为包含“少”或“多”点，并将填充的矩形分类为“短”或“长”。通过识别早期功能性磁共振成像（fMRI）研究中数字比较任务期间显示峰值活动的IPS区域，确定每个个体参与者的刺激部位。与选择作为对照部位的顶点刺激相比，右IPS上的rTMS增加了两项任务的错误率。这一结果表明，正确的IPS的完整性是一个必要条件，不仅为区分数制，但也进行准确的判断的长度。我们建议，这两个过程依赖于一个共同的代表性和/或在正确的IPS机制。(C)2011 Elsevier Srl. All rights reserved.
The critical involvement of the left and right intraparietal sulci (IPS) in numerosity and length processing was tested with neuro-navigated repetitive transcranial magnetic stimulation (rTMS). Participants had to categorize linear arrays of dots as containing "few" or "many" dots, and filled rectangles as "short" or "long". The stimulation sites were determined for each individual participant by identifying the IPS areas showing peak activity during a number comparison task in earlier functional magnetic resonance imaging (fMRI) studies. Compared to the stimulation of the vertex chosen as a control site, rTMS over the right IPS increased the error rate in both tasks. This result indicates that the integrity of the right IPS is a necessary condition not only for discriminating numerosities but also for performing accurate judgements of lengths. We propose that these two processes rely on a common representation and/or mechanism in the right IPS. (C) 2011 Elsevier Srl. All rights reserved.