Human gut microbiota: the links with dementia development.
Human gut microbiota: the links with dementia development.
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人类肠道微生物群：与痴呆症发展的联系
DOI：
10.1007/s13238-016-0338-6
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发表时间：
2017-02
期刊：
影响因子：
21.1
通讯作者：
Zhu B
中科院分区：
文献类型：
--
作者：
Alkasir R;Li J;Li X;Jin M;Zhu B
痴呆症是一种综合性的脑部疾病，足以影响一个人的日常功能。最常见的痴呆类型是阿尔茨海默病，这使得大多数病例。新的研究表明，胃肠道微生物群通过触发代谢性疾病和低度炎症进展与痴呆发病机制直接相关。提出了一种新的策略，用于管理这些疾病，并通过调节微生物群（例如使用益生菌）作为痴呆和其他相关疾病的精神治疗的辅助剂。
Dementia is a comprehensive category of brain diseases that is great enough to affect a person’s daily functioning. The most common type of dementia is Alzheimer’s disease, which makes most of cases. New researches indicate that gastrointestinal tract microbiota are directly linked to dementia pathogenesis through triggering metabolic diseases and low-grade inflammation progress. A novel strategy is proposed for the management of these disorders and as an adjuvant for psychiatric treatment of dementia and other related diseases through modulation of the microbiota (e.g. with the use of probiotics).