Effect of residual patient motion on dose distribution during image-guided robotic radiosurgery for skull tracking based on log file analysis
Effect of residual patient motion on dose distribution during image-guided robotic radiosurgery for skull tracking based on log file analysis
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DOI：
10.1007/s11604-014-0330-0
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发表时间：
2014-08-01
影响因子：
2.1
通讯作者：
Inoue, Tomio
中科院分区：
文献类型：
--
作者：
Inoue, Mitsuhiro;Shiomi, Hiroya;Inoue, Tomio
本研究旨在通过分析系统日志文件，评估颅内图像引导机器人放射外科手术中患者残余运动对剂量分布的影响，根据原始剂量分布和估计剂量分布之间的差异，包括两次连续图像采集之间的患者残余运动引起的靶向误差，分析剂量学影响。分析了128种治疗方法。42例患者采用等中心计划治疗，86例患者采用适形（非等中心）计划治疗，成像中心到靶点的中位距离为55 mm，序列图像采集的中位间隔为79 s。每个轴的平移残余患者运动中位数为0.1 mm，Delta俯仰和Delta滚动的旋转残余患者运动为0.1A度，Delta偏航的旋转残余患者运动为0.2A度。在超过95%的病例中，D（95）的剂量误差在1%以内。D（10）至D（90）的最大剂量误差在2%以内。所研究的参数，包括连续图像采集之间的时间间隔，都与剂量测定效应无显著相关性，剩余患者运动对剂量分布的影响极小。
The present study aimed to assess the effect of residual patient motion on dose distribution during intracranial image-guided robotic radiosurgery by analyzing the system log files.The dosimetric effect was analyzed according to the difference between the original and estimated dose distributions, including targeting error, caused by residual patient motion between two successive image acquisitions. One hundred twenty-eight treatments were analyzed. Forty-two patients were treated using the isocentric plan, and 86 patients were treated using the conformal (non-isocentric) plan.The median distance from the imaging center to the target was 55 mm, and the median interval between the acquisitions of sequential images was 79 s. The median translational residual patient motion was 0.1 mm for each axis, and the rotational residual patient motion was 0.1A degrees for Delta pitch and Delta roll and 0.2A degrees for Delta yaw. The dose error for D (95) was within 1 % in more than 95 % of cases. The maximum dose error for D (10) to D (90) was within 2 %. None of the studied parameters, including the interval between the acquisitions of sequential images, was significantly related to the dosimetric effect.The effect of residual patient motion on dose distribution was minimal.