Optimization of Human Immunodeficiency Virus Treatment During Incarceration Viral Suppression at the Prison Gate
Optimization of Human Immunodeficiency Virus Treatment During Incarceration Viral Suppression at the Prison Gate
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DOI：
10.1001/jamainternmed.2014.601
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发表时间：
2014-05-01
影响因子：
39
通讯作者：
Springer, Sandra A.
中科院分区：
文献类型：
--
作者：
Meyer, Jaimie P.;Cepeda, Javier;Springer, Sandra A.
重要性 惩教机构中的人体免疫缺陷病毒 (HIV) 管理在逻辑上是可行的，但最近尚未对释放前的 HIV 相关结果进行系统检查。 目的 评估整个监禁期间（包括看守所和监狱）的 HIV 治疗结果。 设计、环境和参与者 对康涅狄格州惩教署（2005-2012 年）内 882 名确诊 HIV 的囚犯进行纵向关联的人口统计、药学和实验室数据的回顾性队列研究连续监禁 90 天或更长时间的感染者，至少进行了 2 项 HIV-1 RNA 和 CD4 淋巴细胞测量，并接受了抗逆转录病毒治疗。 主要结果和措施 整合了三个电子数据库（惩教、实验室和药房）来评估 HIV 病毒抑制（HIV-1 RNA 水平、
IMPORTANCE Human immunodeficiency virus (HIV) management in correctional settings is logistically feasible, but HIV-related outcomes before release have not been recently systematically examined.OBJECTIVE To evaluate HIV treatment outcomes throughout incarceration, including jail and prison.DESIGN, SETTING, AND PARTICIPANTS Retrospective cohort study of longitudinally linked demographic, pharmacy, and laboratory data on 882 prisoners within the Connecticut Department of Correction (2005-2012) with confirmed HIV infection, who were continually incarcerated 90 days or more, had at least 2 HIV-1 RNA and CD4 lymphocyte measurements, and were prescribed antiretroviral therapy.MAIN OUTCOMES AND MEASURES Three electronic databases (correctional, laboratory, and pharmacy) were integrated to assess HIV viral suppression (HIV-1 RNA levels,