Efficient synthesis of 2,3-dihydro-1,4-benzoxazines via intramolecular copper-catalyzed O-arylation

Efficient synthesis of 2,3-dihydro-1,4-benzoxazines via intramolecular copper-catalyzed O-arylation
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DOI:
10.1016/j.tetlet.2009.04.055
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发表时间:
2009-07-08
影响因子:
1.8
通讯作者:
Chen, Yuanwei
Chen, Yuanwei
中科院分区:
化学4区
文献类型:
--
作者:
Liu, Zhangqin;Chen, Yuanwei

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A highly efficient synthetic approach to 2,3-dihydro-1,4-benzoxazines is described. The method involves a mild intramolecular copper-catalyzed O-arylation of beta aminoalcohol, which works well without N-protection. (C) 2009 Elsevier Ltd. All rights reserved.