Smartphone-Supported versus Full Behavioural Activation for Depression: A Randomised Controlled Trial.
Smartphone-Supported versus Full Behavioural Activation for Depression: A Randomised Controlled Trial.
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DOI：
10.1371/journal.pone.0126559
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发表时间：
2015
期刊：
影响因子：
3.7
通讯作者：
Andersson G
中科院分区：
文献类型：
--
作者：
Ly KH;Topooco N;Cederlund H;Wallin A;Bergström J;Molander O;Carlbring P;Andersson G
需要更多成本和时间有效的抑郁症治疗方法。这是第一个随机对照试验，其中将混合治疗（包括四次面对面会议和智能手机应用程序）与完整的行为治疗进行比较。因此，本文的目的是检查混合智能手机治疗是否不劣于抑郁症的完全行为激活治疗。这是一项随机对照非劣效性试验 (NCT01819025)，针对重度抑郁症患者，将混合治疗 (n=46) 与完整的十个疗程治疗 (n=47) 进行比较。主要结果指标是 BDI-II，在治疗前和治疗后以及治疗后六个月进行。结果显示，随着时间的推移，两组的主要结局指标均有显着改善（组内 Cohen d=1.35；CI [−0.82, 3.52] 至 d=1.47；CI [−0.41, 3.35]；组间 d=−0.13 CI [−2.37, 2.09] 和 d=−0.10 CI [−2.53， 2.33]）。同时，混合治疗平均减少了 47% 的治疗时间。我们无法确定混合治疗是否不劣于完全 BA 治疗。尽管如此，这项研究指出，通过使用智能手机应用程序作为附加功能，混合治疗方法可能会治疗近两倍的抑郁症患者。在我们证明混合治疗方法是一种有希望的、具有成本效益的替代常规面对面治疗抑郁症的方法之前，还需要进行更多的研究。通过智能手机支持的认知行为疗法治疗抑郁症 NCT01819025
There is need for more cost and time effective treatments for depression. This is the first randomised controlled trial in which a blended treatment - including four face-to-face sessions and a smartphone application - was compared against a full behavioural treatment. Hence, the aim of the current paper was to examine whether a blended smartphone treatment was non-inferior to a full behavioural activation treatment for depression. This was a randomised controlled non-inferiority trial (NCT01819025) comparing a blended treatment (n=46) against a full ten-session treatment (n=47) for people suffering from major depression. Primary outcome measure was the BDI-II, that was administered at pre- and post-treatment, as well as six months after the treatment. Results showed significant improvements in both groups across time on the primary outcome measure (within-group Cohen’s d=1.35; CI [−0.82, 3.52] to d=1.47; CI [−0.41, 3.35]; between group d=−0.13 CI [−2.37, 2.09] and d=−0.10 CI [−2.53, 2.33]). At the same time, the blended treatment reduced the therapist time with an average of 47%. We could not establish whether the blended treatment was non-inferior to a full BA treatment. Nevertheless, this study points to that the blended treatment approach could possibly treat nearly twice as many patients suffering from depression by using a smartphone applica¬tion as add-on. More studies are needed before we can suggest that the blended treatment method is a promising cost-effective alternative to regular face-to-face treatment for depression. Cognitive Behavioral Therapy Treatment of Depression With Smartphone Support NCT01819025
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影响因子：
2.3
作者：
Hopko, DR;Lejuez, CW;McNeil, DW
通讯作者：
McNeil, DW
影响因子：
5.9
作者：
Kennard, Betsy D.;Clarke, Greg N.;Brent, David A.
通讯作者：
Brent, David A.
影响因子：
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作者：
Gueorguieva, R;Krystal, JH
通讯作者：
Krystal, JH
影响因子：
1.5
作者：
Harnett, Paul;O'Donovan, Analise;Lambert, Michael J.
通讯作者：
Lambert, Michael J.
影响因子：
5.9
作者：
JACOBSON, NS;TRUAX, P
通讯作者：
TRUAX, P