Primary anorectal melanoma.
Primary anorectal melanoma.
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DOI：
10.1159/000360814
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发表时间：
2014-01
影响因子：
0.8
通讯作者：
Mirrakhimov AE
中科院分区：
文献类型：
--
作者：
Khan M;Bucher N;Elhassan A;Barbaryan A;Ali AM;Hussain N;Mirrakhimov AE
原发于肛门和直肠的恶性黑色素瘤是一种罕见的侵袭性肿瘤，在病程早期倾向于局部侵袭和转移。它经常被误诊为痔疮或其他良性肛门直肠疾病之一，因此与总体预后不良和5年存活率低于20%有关。最佳的治疗方法仍然存在争议，目前的证据表明腹会切除比广泛的局部切除没有任何更好的生存益处。晚期疾病可采用化疗或放射治疗。我们报告一位71岁女性患者，表现为大便疼痛及便血。她最终被发现在肛门直肠交界处有一个肿块，并有区域淋巴受累。患者接受了腹会切除术，目前正在接受化疗。
Primary malignant melanoma of the anus and rectum is a rare and aggressive neoplasm that tends to invade locally and metastasize early in the course of the disease. It is often misdiagnosed as hemorrhoids or as one of the other benign anorectal conditions and is thus linked to an overall poor prognosis and a 5-year survival rate of less than 20%. Optimal treatment is still controversial, and current evidence does not show any preferential survival benefit from abdominoperineal resection over wide local excision. Chemotherapy or radiotherapy may be used for advanced disease. We report a 71-year-old female presenting with painful bowel movements and blood in stools. She was eventually found to have a mass arising from the anorectal junction with regional lymph node involvement. The patient underwent an abdominoperineal resection and is currently scheduled for chemotherapy.
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影响因子：
3.4
作者：
Hillenbrand, A.;Barth, T. F. E.;Formentini, A.
通讯作者：
Formentini, A.
DOI：
10.1007/s00432-010-0793-z
发表时间：
2010-09-01
影响因子：
3.6
作者：
Zhang, Sen;Gao, Feng;Wan, Desen
通讯作者：
Wan, Desen
影响因子：
6.2
作者：
Kelly, Patrick;Zagars, Gunar K.;Guadagnolo, B. Ashleigh
通讯作者：
Guadagnolo, B. Ashleigh
影响因子：
3.4
作者：
MORSON, BC;VOLKSTADT, H
通讯作者：
VOLKSTADT, H
影响因子：
3.2
作者：
Cheung, Michael C.;Perez, Eduardo A.;Koniaris, Leonidas G.
通讯作者：
Koniaris, Leonidas G.