MAJOR ELECTROCARDIOGRAPHIC ABNORMALITIES IN PERSONS AGED 65 YEARS AND OLDER (THE CARDIOVASCULAR HEALTH STUDY)

MAJOR ELECTROCARDIOGRAPHIC ABNORMALITIES IN PERSONS AGED 65 YEARS AND OLDER (THE CARDIOVASCULAR HEALTH STUDY)
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DOI:
10.1016/0002-9149(92)91231-r
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发表时间:
1992-05-15
影响因子:
2.8
通讯作者:
RAUTAHARJU, PM
RAUTAHARJU, PM
中科院分区:
医学3区
文献类型:
--
作者:
FURBERG, CD;MANOLIO, TA;RAUTAHARJU, PM

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心电图异常常见于老年患者,但其在自由生活的老年人群中的患病率尚不明确。此外,许多这些异常的临床意义是不确定的。心血管健康研究--一项关于老年人中风和冠心病危险因素的研究--确定了5,150名年龄大于或等于65岁的成年人的主要心电图异常的患病率。心室传导缺陷、主要Q/QS波、左心室肥大、孤立性主要ST-T波异常、房颤和一度房室传导阻滞被统称为主要心电图异常。在整个队列中,任何重大心电图异常的患病率为29%,在2,413名没有冠状动脉疾病或全身性高血压病史的参与者中为19%,在2,737名有冠状动脉疾病或高血压病史的参与者中为37%。无论病史如何,男性主要心电图异常的患病率均高于女性,且有随年龄增长而增加的趋势。5.2%的患者出现Q/QS波,其中超过一半的患者既往未报告心肌梗死。主要的心电图异常常见于老年男性和女性,无论是否有心脏病史。
Electrocardiographic abnormalities are often found in older patients, but their prevalence in free-living elderly populations is not well-defined. In addition, the clinical significance of many of these abnormalities is uncertain. The prevalence of major electrocardiographic abnormalities was determined in 5,150 adults aged greater-than-or-equal-to 65 years from the Cardiovascular Health Study - a study of risk factors for stroke and coronary heart disease in the elderly. Ventricular conduction defects, major Q/QS waves, left ventricular hypertrophy, isolated major ST-T-wave abnormalities, atrial fibrillation and first-degree atrioventricular block were collectively categorized as major electrocardiographic abnormalities. Prevalence of any major electrocardiographic abnormality was 29% in the entire cohort, 19% among 2,413 participants who reported no history of coronary artery disease or systemic hypertension, and 37% among 2,737 participants with a history of coronary artery disease or hypertension. Prevalence of major electrocardiographic abnormalities was higher in men than in women regardless of history, and tended to increase with age. Major Q/QS waves were found in 5.2%, and more than half were in those who did not report a previous myocardial infarction. Major electrocardiographic abnormalities are common in elderly men and women irrespective of the history of heart disease.