Secondary ion images of the developing rat brain.
Secondary ion images of the developing rat brain.
复制标题
发育中的大鼠大脑的二次离子图像。
DOI：
10.1016/j.jasms.2004.04.029
复制
发表时间：
2004
影响因子：
3.2
通讯作者：
McCandlishJr,CarlA
中科院分区：
文献类型：
--
作者：
Todd,PeterJ;McMahon,JohnM;McCandlishJr,CarlA
二次离子图像从出生后21天的大鼠脑切片中获得，使用m/z184磷酸胆碱的强度。当与来自同一动物的类似但染色切片的相应光学图像相比时，二次离子图像似乎反映了发育不全的大脑。在发育过程中，髓鞘形成发生在轴突延伸之后。显然，髓鞘形成模糊了分析离子探针的secondarym/z184，磷脂酰胆碱的来源;没有髓鞘形成，二次离子图像显示没有生理特征。
Secondary ion images were obtained from sections of rat brain over a 21 day postnatal period, using the intensity ofm/z184, phosphocholine. When compared with corresponding optical images of similar, but stained sections from the same animal, the secondary ion images appear to reflect less developed brains. During development, myelination occurs after axon extension. Apparently, myelination obscures the source of secondarym/z184, phosphatidylcholine, from the analyzing ion probe; absenting myelination, secondary ion images show no physiological features.