Case of reversible diabetes mellitus in the setting of benign Pheochromocytoma.
Case of reversible diabetes mellitus in the setting of benign Pheochromocytoma.
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DOI：
10.1016/j.jecr.2018.07.003
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发表时间：
2018-12-01
期刊：
影响因子：
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通讯作者：
Hendrickson, Chase
中科院分区：
文献类型：
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作者：
Cha, Jeeyeon;Khurram, Muhammad;Hendrickson, Chase
嗜铬细胞瘤已被证明损害糖耐量，并极少导致显性糖尿病。我们在此报告一例大型嗜铬细胞瘤，患者最近被诊断为糖尿病，尽管肾上腺切除术后高血糖经大剂量胰岛素治疗后完全消失，但仍难以控制。她戏剧性的表现表明，在新发的胰岛素抵抗和高血压患者中需要考虑这种病因学。
Pheochromocytomas have been shown to impair glucose tolerance and, rarely, to precipitate overt diabetes mellitus. We report here a case of a large pheochromocytoma in a woman with a recent diagnosis of diabetes mellitus that proved difficult to control despite high-dose insulin therapy who had complete resolution of her hyperglycemia following adrenalectomy. Her dramatic presentation demonstrates the need to consider this etiology in patients with new-onset insulin resistance and hypertension.