Role of dobutamine stress echocardiography in predicting outcome in 860 patients with known or suspected coronary artery disease.
Role of dobutamine stress echocardiography in predicting outcome in 860 patients with known or suspected coronary artery disease.
复制标题
多巴酚丁胺负荷超声心动图在预测 860 名已知或疑似冠状动脉疾病患者的结局中的作用。
DOI：
10.1161/01.cir.97.15.1474
复制
发表时间：
1998
期刊：
影响因子：
37.8
通讯作者：
J. Seward
中科院分区：
文献类型：
--
作者：
S. Chuah;P. Pellikka;V. Roger;R. McCully;J. Seward
背景
多巴酚丁胺负荷超声心动图越来越多地被用于检测冠状动脉疾病。与临床和静息超声心动图变量相比，关于该测试的增量预后价值(包括半定量的室壁评分)的信息较少。
方法和结果
对860名接受多巴酚丁胺负荷超声心动图检查的患者进行了为期两年的随访。为了确定多巴酚丁胺负荷超声心动图在预测心脏事件(包括心源性死亡和心肌梗死)中的价值，将临床和静息超声心动图资料和负荷超声心动图资料纳入逐步Cox多元回归模型。在长达52个月的随访中，72名患者在发生任何心脏事件之前接受了冠状动脉血管重建术，并进行了审查。86名患者有心脏事件，包括36名非致命性心肌梗死和50名心脏性死亡。在多变量模型中，充血性心力衰竭病史、峰值应激时异常节段的百分比以及左心室收缩末期容量对应激的异常反应是心脏事件的独立预测因素。最能预测后续心脏事件的模型包括临床和负荷超声心动图数据。
结论
多巴酚丁胺负荷超声心动图与半定量节段性室壁评分在预测后续心脏事件方面提供了重要的增量信息。
BACKGROUND
Increasingly, dobutamine stress echocardiography has been used for detection of coronary artery disease. Less information exists regarding the incremental prognostic value of the test, including semiquantitative wall scoring, compared with clinical and rest echocardiographic variables.
METHODS AND RESULTS
Follow-up information was obtained from 860 patients who underwent dobutamine stress echocardiography over a 2-year period. To determine the value of dobutamine stress echocardiography in predicting cardiac events, including cardiac death and myocardial infarction, clinical and rest and stress echocardiographic data were considered in a stepwise Cox multivariate regression model. During follow-up of up to 52 months, 72 patients underwent coronary revascularization before any cardiac event and were censored. Eighty-six patients had cardiac events, including nonfatal myocardial infarction in 36 and cardiac death in 50. In a multivariate model, a history of congestive heart failure, the percentage of abnormal segments at peak stress, and an abnormal left ventricular end-systolic volume response to stress were independent predictors of cardiac events. The model that best predicted subsequent cardiac events included clinical and stress echocardiographic data.
CONCLUSIONS
Dobutamine stress echocardiography with semiquantitative segmental wall scoring provides important incremental information in predicting subsequent cardiac events.
多巴酚丁胺负荷超声心动图可预测主动脉瘤和周围血管疾病患者的手术结果。
影响因子：
24
作者：
Dávila-Román,VG;Waggoner,AD;Sicard,GA;Geltman,EM;Schechtman,KB;Pérez,JE
通讯作者：
Pérez,JE
多巴酚丁胺负荷超声心动图：敏感性、特异性和对未来心脏事件的预测价值。
影响因子：
4.8
作者：
Afridi,I;Quiñones,MA;Zoghbi,WA;Cheirif,J
通讯作者：
Cheirif,J