Fetal and fetal organ volume estimations with magnetic resonance imaging
Fetal and fetal organ volume estimations with magnetic resonance imaging
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DOI：
10.1016/s0002-9378(96)70159-x
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发表时间：
1996-08-01
影响因子：
9.8
通讯作者：
Roberts, N
中科院分区：
文献类型：
--
作者：
Garden, AS;Roberts, N
目的：我们的目的是利用卡瓦列里体视学方法和点计数技术来估计胎儿、胎儿大脑、胎儿肝脏和胎儿肺的体积。研究设计：从 27 周到足月，对四位妊娠进行了 3 至 5 次研究。结果：在所研究的四个胎儿中，胎儿总体积以每天 19.0 至 30.8 毫升的速度增加。胎儿肝脏占胎儿总体积的2.5%至4.9%；胎儿肺，2.5%至4.4%；胎儿大脑为11.5%至16.9%。胎儿肝脏的大小每天增加0.4至1.3毫升；肺部，1.2至1.4毫升/天；和胎儿大脑，每天 2.7 至 3.8 毫升。胎儿脑/肝比率在 2.4 至 5.6 之间，可能是不对称生长模式的指标，并且随着妊娠的增加，比率有下降的趋势。 结论：这是第一个利用磁共振成像和体视学对胎儿总体积和胎儿器官体积进行的系列研究。与超声检查获得的二维测量相比，测量胎儿总体积和胎儿器官的差异生长可能是评估胎儿宫内生长的更灵敏的方法。
OBJECTIVE: Our purpose was to estimate, with the Cavalieri method of stereology and a point-counting technique, the volume of the fetus, fetal brain, fetal liver, and fetal lungs.STUDY DESIGN: Four pregnancies were studied on three to five occasions at gestations from 27 weeks until term.RESULTS: In the lour fetuses studied the total fetal volume increased at a rate of between 19.0 and 30.8 ml/day. The fetal liver constituted 2.5% to 4.9% of the total fetal volume; the fetal lung, 2.5% to 4.4%; and the fetal brain, 11.5% to 16.9%. The fetal liver increased in size by 0.4 to 1.3 ml/day; the lungs, by 1.2 to 1.4 ml/day; and the fetal brain, by 2.7 to 3.8 ml/day. The fetal brain/liver ratio, which may be an indicator of an asymmetric growth pattern, was between 2.4 and 5.6 with a tendency to a decreased ratio with increasing gestation.CONCLUSION: This is the first serial study of total fetal volume and fetal organ volume with magnetic resonance imaging and stereology. Measurement of the total fetal volume and differential growth of fetal organs may be a more sensitive method of assessing fetal intrauterine growth than two-dimensional measurements obtained with ultrasonography.