Gastric emptying and pancreatic polypeptide response to carbohydrate meals.
Gastric emptying and pancreatic polypeptide response to carbohydrate meals.
复制标题
胃排空和胰多肽对碳水化合物膳食的反应。
DOI：
10.1007/bf01318371
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发表时间：
1985
影响因子：
3.1
通讯作者：
Meyer,JH
中科院分区：
文献类型：
--
作者：
Taylor,IL;Gulsrud,PO;Elashoff,J;Chew,P;Meyer,JH
本研究探讨胰腺多肽反应等热量餐的放射性标记的葡萄糖或淀粉在6个正常和7迷走神经切断的主题。受试者直立和仰卧时摄入液体葡萄糖餐，淀粉餐以溶液和固体球的形式以直立姿势摄入。在正常受试者中，每餐以相似的速率离开胃，并且由此产生的胰腺多肽反应彼此之间没有显著差异。排空率在迷走神经切断的受试者中明显不同，这取决于摄入的碳水化合物的物理一致性和患者的姿势。尽管存在这些差异，但每餐的胰腺多肽反应几乎相同。这些研究表明，胰多肽对碳水化合物膳食的反应在迷走神经切断术后几年仍然存在，并且不受迷走神经切断术后胃排空率变化以及摄入碳水化合物的物理一致性和化学性质的影响。
This study examined pancreatic polypeptide responses to isocaloric meals of radioactively labeled glucose or starch in six normal and seven vagotomized subjects. Liquid glucose meals were ingested with the subject both erect and supine and starch meals were ingested in the upright posture as a solution and as solid balls. In normal subjects, each meal left the stomach at a similar rate and the resultant pancreatic polypeptide responses were not significantly different from one another. Emptying rates varied markedly in vagotomized subjects depending upon the physical consistency of the carbohydrate ingested and the patient's posture. Despite these differences, pancreatic polypeptide responses to each meal were almost identical. These studies demonstrate that the pancreatic polypeptide response to carbohydrate meals is still present several years after vagotomy and is unaffected by alterations in the rate of gastric emptying after vagotomy and by the physical consistency and chemical nature of the carbohydrate ingested.