Elevated nitric oxide levels associated with hepatic cell apoptosis during liver injury
Elevated nitric oxide levels associated with hepatic cell apoptosis during liver injury
复制标题
肝损伤期间一氧化氮水平升高与肝细胞凋亡相关
DOI:
10.1111/hepr.12783
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发表时间:
2017-02
影响因子:
4.2
通讯作者:
Yang Shulong
中科院分区:
文献类型:
--
作者:
Liu Hui;Li Qian;Wang Ying;Hong Huimin;Chen Mengting;Wang Yingyi;Hong Fenfang;Yang Shulong
Hepatic injury is a major event in liver surgery such as liver transplantation and it always leads to hepatic cell apoptosis. Nitric oxide (NO) is a key signaling regulation molecule. Many researchers have shown that increased NO level can influence liver cell apoptosis by promoting or inhibiting the relative signaling pathways that are involved in the caspase family, Bax/Bcl‐2, mitochondria, oxidative stress, death receptors, and mitogen‐activated protein kinases. Elucidating the relationships between NO and hepatic cell apoptosis is necessary for ameliorating prognosis of liver surgery. This article reviews the newest research progress in the relationships between higher NO levels and hepatic cell apoptosis in liver injury.
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DOI:
10.3760/cma.j.issn.2095-4352.2014.06.002
发表时间:
2014-06
影响因子:
--
作者:
Hongxing Guo;Ke Gao;L. Luo;Qingwen Deng;Yanping Zhang;Jie Luo;Lian-Zhong Liu
通讯作者:
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影响因子:
4.6
作者:
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影响因子:
4.3
作者:
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DOI:
10.3923/pjbs.2011.976.983
发表时间:
2011-11
期刊:
Pakistan journal of biological sciences : PJBS
影响因子:
--
作者:
D. Fouad;F. Ataya;J. Muntané
通讯作者:
D. Fouad;F. Ataya;J. Muntané
影响因子:
3.1
作者:
Liu, Liang-Ming;Zhang, Ji-Xiang;Sun, Sui-Lin
通讯作者:
Sun, Sui-Lin