Tributylphosphine-catalyzed Acylation of Alcohol by Active Ester Directed toward Effective End-capping of Pseudorotaxane Consisting of Ammonium Group and Crown Ether
Tributylphosphine-catalyzed Acylation of Alcohol by Active Ester Directed toward Effective End-capping of Pseudorotaxane Consisting of Ammonium Group and Crown Ether
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三丁基膦催化活性酯对醇的酰化可有效封端由铵基和冠醚组成的拟轮烷
DOI：
10.1246/cl.2002.924
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发表时间：
2002
影响因子：
1.6
通讯作者：
T. Takata
中科院分区：
文献类型：
--
作者：
N. Kihara;Naohisa Nakakoji;T. Takata
根据使用苯甲醇的模型研究结果，在三丁基膦存在下，用S-2-吡啶基3,5-二甲基硫代苯甲酸酯酰化轴上具有末端羟基的拟轮烷，生成轮烷，收率85%。通过该方法很容易合成光学活性的[2]轮烷和[3]轮烷。
According to the results of a model study using benzyl alcohol, pseudorotaxane with terminal hydroxy group on the axle was acylated with S-2-pyridyl 3,5-dimethylthiobenzoate in the presence of tributylphosphine to produce rotaxane in 85% yield. Optically active [2]rotaxane and [3]rotaxane were readily synthesized by this method.