Imine Macrocycle with a Deep Cavity: Guest-Selected Formation of syn/anti Configuration and Guest-Controlled Reconfiguration
Imine Macrocycle with a Deep Cavity: Guest-Selected Formation of syn/anti Configuration and Guest-Controlled Reconfiguration
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DOI：
10.1002/chem.201405912
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发表时间：
2015-02-09
影响因子：
4.3
通讯作者：
Jiang, Wei
中科院分区：
文献类型：
--
作者：
He, Zhenfeng;Ye, Gang;Jiang, Wei
动态共价键是构建大而坚固的有机结构的理想键合之一。在本文中，我们展示了有机模板如何有效地将复杂的动态亚胺库转化为动态亚胺大环。不仅结构得到很好的控制，而且顺/反主体构型被有效地选择，甚至客体在主体的不对称腔中的取向也可以很好地对准。这归因于主客体之间的多重非共价相互作用的微妙平衡和合作。通过顺序添加三个客人在适当的数量，控制动态共价结构的结构重构已首次实现。
A dynamic covalent bond is one of the ideal linkages for the construction of large and robust organic architectures. In the present article, we show how organic templates can efficiently transform a complex dynamic imine library into a dynamic imine macrocycle. Not only is the constitution well controlled, but also the syn/anti host configuration is efficiently selected and even the orientation of the guest in the asymmetric cavity of the host can be well aligned. This is attributed to the delicate balance and the cooperation of multiple noncovalent interactions between the hosts and the guests. Through sequential additions of three guests in appropriate amounts, controlled structural reconfiguration of dynamic covalent architectures has been achieved for the first time.