Balloon pulmonary angioplasty vs. pulmonary endarterectomy in patients with chronic thromboembolic pulmonary hypertension: a systematic review and meta-analysis
Balloon pulmonary angioplasty vs. pulmonary endarterectomy in patients with chronic thromboembolic pulmonary hypertension: a systematic review and meta-analysis
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慢性血栓栓塞性肺动脉高压患者的球囊肺血管成形术与肺动脉内膜切除术：系统评价和荟萃分析
DOI：
10.1007/s10741-020-10070-w
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发表时间：
2021-02-05
影响因子：
4.6
通讯作者：
Zhang, Min
中科院分区：
文献类型：
--
作者：
Zhang, Liyan;Bai, Yuping;Zhang, Min
尽管球囊肺血管成形术（BPA）和肺动脉内膜切除术（PEA）治疗慢性血栓栓塞性肺动脉高压（CTEPH）有效，但其疗效和安全性的比较尚不清楚。我们通过PubMed、Cochrane Library和Embase的系统综述来确定研究，并使用随机效应荟萃分析模型来综合加权平均差异或综合效应大小的估计。本次荟萃分析共纳入54项研究。BPA组围手术期/住院期、2年、3年生存率分别为100%、99%、97%，PEA组分别为93%、90%、88%。随访1 ~ 6个月时，BPA组6分钟步行距离变化量为141.80 m， PEA组为100.73 m。随访12个月，BPA组平均肺动脉压变化值分别为- 18.31、- 17.00、- 12.97 mmHg， PEA组平均肺动脉压变化值分别为- 18.93、- 21.21、- 21.35 mmHg。在
Although balloon pulmonary angioplasty (BPA) and pulmonary endarterectomy (PEA) are effective in chronic thromboembolic pulmonary hypertension (CTEPH), the comparison of their efficacy and safety is still unclear. We identified studies through a systematic review of PubMed, Cochrane Library, and Embase and used a random effects meta-analysis model to synthesize estimates of weighted mean differences or combined effect size. In total, 54 studies were included in this meta-analysis. The survival rates at perioperative/in-hospital period, 2 years, and 3 years were 100%, 99%, and 97%, respectively, in BPA group and 93%, 90%, and 88%, respectively, in PEA group. The variation of 6-min walk distance was 141.80 m in BPA and 100.73 m in PEA when the follow-up was 1-6 months. At 12-month follow-up, the changed results of mean pulmonary arterial pressure were - 18.31, - 17.00, and - 12.97 mmHg in BPA group and - 18.93, - 21.21, and - 21.35 mmHg in PEA group. At