Endoscopic and clinical analysis of primary T-cell lymphoma of the gastrointestinal tract according to pathological subtype
Endoscopic and clinical analysis of primary T-cell lymphoma of the gastrointestinal tract according to pathological subtype
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DOI：
10.1111/jgh.12471
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发表时间：
2014-05-01
影响因子：
4.1
通讯作者：
Myung, Seung-Jae
中科院分区：
文献类型：
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作者：
Kim, Do Hoon;Lee, Danbi;Myung, Seung-Jae
背景与目的对原发性胃肠道t细胞淋巴瘤（PGITL）的临床病理特征了解甚少。本研究评估PGITL病理亚型的临床和内镜特征。方法对36例pdgl患者的42个病变进行评估，其中15例为肠病相关t细胞淋巴瘤（EATL）， 13例为外周t细胞淋巴瘤（PTCL）， 10例为NK/ t细胞淋巴瘤（NK/TL）， 4例为间变性大细胞淋巴瘤（ALCL）。结果sptcl多发于胃和十二指肠，NK/TL多发于小肠和大肠（P=0.009）。四种亚型的内镜特征相似（P=0.124）。41例病变中有15例（36.6%）EBV阳性，NK/TL型EBV阳性的发生率高于其他类型(P
Background and AimLittle is known about the clinicopathological characteristics of primary gastrointestinal T-cell lymphomas (PGITL). This study evaluated the clinical and endoscopic features of the pathological subtypes of PGITL.MethodsForty-two lesions in 36 patients with PGITL were assessed, including 15 enteropathy-associated T-cell lymphomas (EATL), 13 peripheral T-cell lymphomas (PTCL), 10 NK/T-cell lymphomas (NK/TL), and four anaplastic large cell lymphomas (ALCL).ResultsPTCL occurred more frequently in the stomach and duodenum and NK/TL more frequently in the small and large intestines (P=0.009). The endoscopic features of the four subtypes were similar (P=0.124). Fifteen of 41 lesions (36.6%) were Epstein-Barr virus (EBV) positive, with NK/TL more likely to be EBV positive than the other types (P