Tandem indole C-H alkenylation/arylation for tetra-substituted alkene synthesis.
Tandem indole C-H alkenylation/arylation for tetra-substituted alkene synthesis.
复制标题
DOI：
10.1039/c1cc13094c
复制
发表时间：
2011-07
影响因子：
4.9
通讯作者：
L. L. Suarez-L.;M. Greaney
中科院分区：
文献类型：
--
作者：
L. L. Suarez-L.;M. Greaney
炔基吲哚经历了钯催化的吲哚C-H活化/炔碳歧化/芳基化，二芳碘盐提供芳基成分的新序列。以良好到极好的产率制备了一系列官能化的吲哚烯烃，反应对Z-烯烃是选择性的。
Alkynyl indoles undergo a novel sequence of Pd-catalysed indole C-H activation/alkyne carbopalladation/arylation, with diaryliodonium salts providing the aryl components. An array of functionalised indole alkenes have been prepared in good to excellent yield, with the reaction being selective for the Z-alkene.