RAPID LIGHT-INDUCED DECREASE IN PINEAL SEROTONIN N-ACETYLTRANSFERASE ACTIVITY
RAPID LIGHT-INDUCED DECREASE IN PINEAL SEROTONIN N-ACETYLTRANSFERASE ACTIVITY
复制标题
DOI：
10.1126/science.177.4048.532
复制
发表时间：
1972-01-01
期刊：
影响因子：
56.9
通讯作者：
WELLER, JL
中科院分区：
文献类型：
--
作者：
KLEIN, DC;WELLER, JL
光通过眼睛的方式使黑暗诱导的大鼠松果体中5-羟色胺N-乙酰转移酶的活性降低，减半的时间约为3分钟。这种效应是已知的代谢生物胺的任何酶的活性发生的较快的生理变化之一，似乎解释了夜间光照导致松果体5-羟色胺浓度迅速增加的原因。
Light acting by way of the eye causes the dark-induced activity of serotoninN-acetyltransferase in the pineal gland of the rat to decrease with a halving time of about 3 minutes. This effect, which is one of the more rapid physiological changes known to occur in the activity of any enzyme that metabolizes biogenic amines, appears to explain the rapid increase in the concentration of pineal serotonin that is caused by light exposure at night.