Dynamic Looping Interactions: Setting the 3D Stage for the Macrophage.
Dynamic Looping Interactions: Setting the 3D Stage for the Macrophage.
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动态循环交互：为巨噬细胞设置 3D 阶段。
DOI：
10.1016/j.molcel.2017.09.011
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发表时间：
2017
期刊：
影响因子：
16
通讯作者：
Phillips-Cremins,JenniferE
中科院分区：
文献类型：
--
作者：
Rege,Mayuri;Phillips-Cremins,JenniferE
3D 染色质环相互作用介导细胞类型特异性基因表达的机制是一个活跃的研究领域。在本期《分子细胞》中，Phanstiel 等人。 (2017) 注释了巨噬细胞发育过程中的五类循环，并预测了参与其调节的候选因素。
The mechanisms by which 3D chromatin looping interactions mediate cell type-specific gene expression are an active area of investigation. In this issue ofMolecular Cell, Phanstiel et al. (2017) annotate five classes of loops during macrophage development and predict candidate factors involved in their regulation.