Neural bases of focusing attention in working memory: An fMRI study based on group differences
Neural bases of focusing attention in working memory: An fMRI study based on group differences
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DOI：
10.3758/cabn.7.2.130
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发表时间：
2007-06-01
影响因子：
2.9
通讯作者：
Osaka, Naoyuki
中科院分区：
文献类型：
--
作者：
Osaka, Mariko;Komori, Mie;Osaka, Naoyuki
利用功能磁共振成像，我们研究了工作记忆中集中注意力的神经基质。为了探讨这种聚焦效应，我们进行了聚焦和非聚焦两种阅读广度测验。在焦点词中，要保持的目标词是句子中的焦点词。在非焦点句中，目标词不是句子中的焦点词。在这两种条件下，显着激活被发现在三个主要区域：左背外侧前额叶皮层（DLPFC），前扣带皮层（ACC），和左上级顶叶小叶（SPL）。此外，在NF-κ B条件下，左侧SPL的fMRI信号变化增加。这些结果表明，集中注意的神经基质是基于SPL和ACC-DLPFC网络。此外，高跨度和低跨度被试的聚焦效应存在组间差异：高跨度被试的聚焦效应（SPL控制支持）大于低跨度被试。
Using fMRI, we investigated neural substrates for focusing attention in working memory. To explore this focusing effect, two kinds of reading span test (RST), focused and nonfocused, were performed. In the focused RST (F-RST), the target word to be maintained was the focus word in the sentence. In the nonfocused RST (NF-RST), the target word was not the focus word in the sentence. In both RST conditions, significant activations were found in three main regions: left dorsolateral prefrontal cortex (DLPFC), anterior cingulate cortex (ACC), and left superior parietal lobule (SPL). In addition, fMRI signal changes increased in the left SPL in the NF-RST condition. These findings suggest that the neural substrates of focusing attention are based on SPL and ACC-DLPFC networks. Furthermore, there were group differences in the focusing effect between high-span and low-span subjects: High-span subjects showed focusing effects (supported by SPL control) greater than those of low-span subjects.