Anxiety in epilepsy: A neglected disorder
Anxiety in epilepsy: A neglected disorder
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DOI：
10.1016/j.jpsychores.2014.12.002
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发表时间：
2015-02-01
影响因子：
4.7
通讯作者：
Mohamed, Armin
中科院分区：
文献类型：
--
作者：
Gandy, Milena;Sharpe, Louise;Mohamed, Armin
目的：焦虑症和症状是癫痫患者（PWE）中非常普遍和有问题的合并症，但它们仍然知之甚少，往往未被发现。本研究的目的是进一步了解PWE中的焦虑。方法：研究1评估了常用但未经验证的测量方法的有效性（医院焦虑抑郁量表-焦虑子量表; HADS-A）对147名门诊成人癫痫患者进行DSM-IV焦虑障碍的识别。这项研究发现，虽然HADS-A具有合理的特异性（75%），其敏感性差（61%）和曲线下面积不足（.68）认为它作为这一人群中焦虑症的筛查者是不可靠的。研究2的目的是进一步了解焦虑症之间的关系，定义为临床访谈，和心理社会相关的PWE。研究1的122名参与者完成了一系列心理社会测量。结果：多变量分析显示，焦虑症的存在与失业有关，这被发现是唯一的独立预测因素。也就是说，尽管事实上，心理社会因素共同促成的方差焦虑disorders.Conclusion：这些研究结果添加到文献表明，HADS可能表明困扰，但没有充分确定人与焦虑症，并强调迫切需要发展一个可靠的焦虑筛查措施PWE。此外，结果表明，PWE焦虑症可能是多方面的心理社会因素，需要进一步调查。(c)2014爱思唯尔公司All rights reserved.
Objective: Anxiety disorders and symptoms are highly prevalent and problematic comorbidities in people with epilepsy (PWE), yet they remain poorly understood and often go undetected. This research aimed to further our understanding about anxiety in PWE.Methods: Study 1 assessed the effectiveness of the commonly utilised yet unvalidated measure (Hospital Anxiety Depression Scale-Anxiety subscale; HADS-A) to identify DSM-IV anxiety disorders in 147 adult epilepsy outpatients.Results: This study found that although the HADS-A had reasonable specificity (75%), its poor sensitivity (61%) and inadequate area under the curve (.68) deemed it unreliable as a screener for anxiety disorders in this population.Methods: Study 2 aimed to further our understanding of the relationship between anxiety disorders, as defined by clinical interview, and psychosocial correlates in PWE. One hundred and twenty-two participants from Study 1 completed a battery of psychosocial measures.Results: Multivariate analysis revealed that the presence of an anxiety disorder was associated with unemployment, which was found to be the only independent predictor. That is, despite the fact that psychosocial factors together contributed to the variance in anxiety disorders none were revealed to be significant independent predictors.Conclusion: These findings add to the literature indicating that the HADS may indicate distress, but does not adequately identify people with anxiety disorders and highlights the urgent need for the development of a reliable anxiety screening measure for PWE. Further, the results suggest that anxiety disorders in PWE are likely to be multiply determined with respect to psychosocial factors and require further investigation. (c) 2014 Elsevier Inc. All rights reserved.