Early neonatal brain injury in histologic chorioamnionitis

Early neonatal brain injury in histologic chorioamnionitis
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DOI:
10.1067/mpd.2001.109605
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发表时间:
2001-01-01
影响因子:
5.1
通讯作者:
Bracci, R
Bracci, R
中科院分区:
医学2区
文献类型:
--
作者:
De Felice, C;Toti, P;Bracci, R

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研究了临床或组织学绒毛膜炎与早期新生儿不良神经学结局之间的关系(n = 483)。组织学而非临床的绒毛膜炎证据被认为是每心室回声密度的重要预测因素(比值比,2.4; 95% CI,1.8-3.2),回声透明(3.3; 1.9-5.6)、脑室扩大(2.7; 1.8-4.2)、脑室内出血≥ 3(3.5; 2.4-5.2)和癫痫发作(2.3; 1.4-3.7)。
The relation between clinical or histologic chorioamnionitis and early neonatal adverse neurologic outcome was investigated (n = 483). Histologic, but not clinical, evidence of chorioamnionitis was found to be a significant predictor of per;ventricular echodensity (odds ratio, 2.4; 95% CI, 1.8-3.2), echolucency (3.3; 1.9-5.6), ventriculomegaly (2.7; 1.8-4.2), intraventricular hemorrhage greater than or equal to3 (3.5; 2.4-5.2), and seizures (2.3; 1.4-3.7).