Visualization of swallowing using real-time TrueFISP MR fluoroscopy
Visualization of swallowing using real-time TrueFISP MR fluoroscopy
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DOI：
10.1007/s00330-001-1146-8
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发表时间：
2002-01-01
影响因子：
5.9
通讯作者：
Debatin, JF
中科院分区：
文献类型：
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作者：
Barkhausen, J;Goyen, M;Debatin, JF
本研究的目的是评估不同的稳定进动实时真快速成像 (TrueFISP) 序列描述吞咽过程和描绘吞咽困难患者口咽病理的能力。使用配备高性能梯度（振幅 40 mT/m）的 1.5 T 扫描仪（Magnetom Sonata，西门子，德国埃尔兰根）对 8 名志愿者和 6 名吞咽困难患者进行实时 TrueFISP 吞咽可视化。评估了四种不同实时 TrueFISP 序列（TR 2.2-3.0 ms、TE 1.1-1.5 ms、矩阵 63x128-135x256、视场 250 mm(2)、每幅图像采集时间 139-405 ms）的图像质量。水、酸奶和粗面粉布丁被评估为口服造影剂。使用最快的实时 TrueFISP 序列（TR 2.2 ms，TE 1.1 ms，矩阵 63x128）可以最好地对口咽装置进行功能探索。采集时间的增加导致解剖结构模糊。由于 TrueFISP 序列的图像对比度取决于 T2/T1 特性，因此所有测试的食品都非常适合作为口服造影剂，但使用粗面粉布丁的图像质量最好。使用实时 TrueFISP 序列结合口服造影剂可以实现吞咽的实时可视化。对于吞咽功能的探索，高时间分辨率比空间分辨率更重要。
The aim of this study was to evaluate the ability of different real-time true fast imaging with steady precession (TrueFISP) sequences regarding their ability to depict the swallowing process and delineate oropharyngeal pathologies in patients with dysphagia. Real-time TrueFISP visualization of swallowing was performed in 8 volunteers and 6 patients with dysphagia using a 1.5 T scanner (Magnetom Sonata, Siemens, Erlangen Germany) equipped with high-performance gradients (amplitude 40 mT/m). Image quality of four different real-time TrueFISP sequences (TR 2.2-3.0 ms, TE 1.1-1.5 ms, matrix 63x128-135x256, field of view 250 mm(2), acquisition tithe per image 139-405 ms) was evaluated. Water, yoghurt, and semolina pudding were assessed as oral contrast agents. Functional exploration of the oropharyngeal apparatus was best possible using the fastest real-time TrueFISP sequence (TR 2.2 ms, TE 1.1 ms, matrix 63x128). Increased acquisition time resulted in blurring of anatomical structures. As the image contrast of TrueFISP sequences depends on T2/T1 properties, all tested foodstuff were well suited as oral contrast agents, but image quality was best using semolina pudding. Real-time visualization of swallowing is possible using real-time TrueFISP sequences in conjunction with oral contrast agents. For the functional exploration of swallowing high temporal resolution is more crucial than spatial resolution.