Sampling, identification and sensory evaluation of odors of a newborn baby’s head and amniotic fluid

Sampling, identification and sensory evaluation of odors of a newborn baby’s head and amniotic fluid
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DOI:
10.1038/s41598-019-49137-6
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发表时间:
2019-09
期刊:
影响因子:
4.6
通讯作者:
T. Uebi;T. Hariyama;Kazunao Suzuki;N. Kanayama;Y. Nagata;S. Ayabe‐Kanamura;S. Yanase;Y. Ohtsubo;M. Ozaki
T. Uebi;T. Hariyama;Kazunao Suzuki;N. Kanayama;Y. Nagata;S. Ayabe‐Kanamura;S. Yanase;Y. Ohtsubo;M. Ozaki
中科院分区:
综合性期刊3区
文献类型:
--
作者:
T. Uebi;T. Hariyama;Kazunao Suzuki;N. Kanayama;Y. Nagata;S. Ayabe‐Kanamura;S. Yanase;Y. Ohtsubo;M. Ozaki

文献摘要

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对于婴儿气味分析,无创、无压力的样本收集非常重要。使用一种简单的方法,我们成功地从五个新生儿的头部获得了新鲜的气味。这些气味通过二维气相色谱-质谱联用(GC × GC-MS)进行化学分析,并相互比较或与婴儿母亲的羊水气味进行比较。我们确定了31种化学成分的挥发性气味从新生儿头部和21个从羊水。虽然其中15种成分在两种来源中是共同的,但头部气味和羊水气味之间的GC × GC模式存在明显差异,因此新生儿头部气味可能在出生后立即单独不同。因此,我们将新生儿头部和母体羊水的主要气味成分人工混合,并使用心理测试来检查这些气味是否可以相互区分。我们的数据表明,人工气味的新生儿头部可以区分羊水,和气味的人工头部气味混合物可以正确区分新生儿出生后1小时内,在2或3天的年龄。
For baby odor analyses, noninvasive, stress-free sample collection is important. Using a simple method, we succeeded in obtaining fresh odors from the head of five newborn babies. These odors were chemically analyzed by two-dimensional gas chromatography coupled with mass spectrometry (GC × GC-MS), and compared with each other or with the odor of amniotic fluid from the baby’s mother. We identified 31 chemical components of the volatile odors from neonate heads and 21 from amniotic fluid. Although 15 of these components were common to both sources, there was an apparent difference in the GC × GC patterns between the head and amniotic fluid odors, so the neonate head odor might be individually distinct immediately after birth. Therefore, we made artificial mixtures of the major odor components of the neonate head and maternal amniotic fluid, and used psychological tests to examine whether or not these odors could be distinguished from each other. Our data show that the artificial odor of a neonate head could be distinguished from that of amniotic fluid, and that the odors of artificial head odor mixtures could be correctly discriminated for neonates within an hour after birth and at 2 or 3 days of age.