A controlled randomized study examining the effects of exercise therapy on patients undergoing haematopoietic stem cell transplantation
A controlled randomized study examining the effects of exercise therapy on patients undergoing haematopoietic stem cell transplantation
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DOI：
10.1038/bmt.2009.163
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发表时间：
2010-02-01
影响因子：
4.8
通讯作者：
Fauser, A. A.
中科院分区：
文献类型：
--
作者：
Baumann, F. T.;Kraut, L.;Fauser, A. A.
造血干细胞移植（HSCT）可引起严重的副作用，这可能对患者的身体和心理生活产生深远的影响。一些研究表明，体力活动对HSCT后的住院患者有积极影响。因此，问题是，从条件反射阶段一开始就进行有控制的锻炼计划是否有助于患者的身心康复。为了评估特定的，适度的体力活动对HSCT患者的身体和心理状况的不同影响，我们对64例接受同种异体或自体HSCT的住院患者进行了一项对照随机研究。将患者随机分为两组。虽然训练组在整个住院期间每天两次参加一个特定的运动疗法方案，但对照组的患者接受医院的标准动员方案。这项研究的结果显示，在力量、耐力、肺功能和生活质量方面，训练组有显著差异。然而，需要进一步的研究来证实这些结果。骨髓移植（2010）45，355-362; doi：10.1038/bmt.2009.163; 2009年7月13日在线发表
A haematopoietic SCT (HSCT) can cause severe side effects, which may have a profound impact on a patient's life both physically and psychologically. Some studies have shown that physical activity has positive effects for inpatients after an HSCT. Therefore, the question arises whether a controlled exercise programme right from the beginning of the conditioning phase could help contribute to a patient's physical and psychological recovery. To evaluate the different effects of specific, moderate physical activities on the physical and psychological condition of HSCT patients we performed a controlled randomized study with 64 inpatients undergoing an allogeneic or autologous HSCT. The patients were randomly assigned to two groups. Although the training group took part in a specific programme of exercise therapy twice a day throughout the entire hospitalization phase, patients in the control group were offered the hospital's standard mobilization programme. The results of this study showed significant differences in favour of the training group regarding strength, endurance, lung function and quality of life. However, further studies are needed to confirm these results. Bone Marrow Transplantation (2010) 45, 355-362; doi:10.1038/bmt.2009.163; published online 13 July 2009