A heavy burden on young minds: the global burden of mental and substance use disorders in children and youth.
A heavy burden on young minds: the global burden of mental and substance use disorders in children and youth.
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DOI：
10.1017/s0033291714002888
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发表时间：
2015-05
影响因子：
6.9
通讯作者：
Scott JG
中科院分区：
文献类型：
--
作者：
Erskine HE;Moffitt TE;Copeland WE;Costello EJ;Ferrari AJ;Patton G;Degenhardt L;Vos T;Whiteford HA;Scott JG
精神和物质使用障碍很常见，而且往往持续存在，许多在生命早期出现。与成人精神和物质使用障碍相比，儿童和青年因这些疾病造成的全球负担得到的关注相对较少。来自2010年全球疾病负担研究的数据用于调查0-24岁儿童和青年的精神和物质障碍负担。根据残疾调整生命年（DALYs）估算负担，DALYs来自残疾生活年数（YLDs）和生命损失年数（YLLs）的总和。在全球范围内，精神和药物使用障碍是导致儿童和青年残疾的主要原因，占所有儿童和青年残疾人数（5420万）的四分之一。就DALYs而言，他们以5550万DALYs（5.7%）排名第6，当重新归因于自杀死亡负担时，他们升至第5位。在高收入国家，精神和药物使用障碍是伤残调整生命年的主要原因，但在低收入和中等收入国家，由于传染病导致的死亡率，它们排在第七位。精神和物质使用障碍是造成全球儿童和青年疾病负担的重要因素。随着中低收入国家生殖健康和传染病管理的改善，精神和药物使用失调在儿童和青年疾病负担中所占的比例将会增加，因此需要重新调整这些国家的保健服务。
Mental and substance use disorders are common and often persistent, with many emerging in early life. Compared to adult mental and substance use disorders, the global burden attributable to these disorders in children and youth has received relatively little attention. Data from the Global Burden of Disease Study 2010 was used to investigate the burden of mental and substance disorders in children and youth aged 0–24 years. Burden was estimated in terms of disability-adjusted life years (DALYs), derived from the sum of years lived with disability (YLDs) and years of life lost (YLLs). Globally, mental and substance use disorders are the leading cause of disability in children and youth, accounting for a quarter of all YLDs (54.2 million). In terms of DALYs, they ranked 6th with 55.5 million DALYs (5.7%) and rose to 5th when mortality burden of suicide was reattributed. While mental and substance use disorders were the leading cause of DALYs in high-income countries (HICs), they ranked 7th in low- and middle-income countries (LMICs) due to mortality attributable to infectious diseases. Mental and substance use disorders are significant contributors to disease burden in children and youth across the globe. As reproductive health and the management of infectious diseases improves in LMICs, the proportion of disease burden in children and youth attributable to mental and substance use disorders will increase, necessitating a realignment of health services in these countries.