Hepatoblastoma in the Nordic countries
Hepatoblastoma in the Nordic countries
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DOI:
10.1002/ijc.27351
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发表时间:
2012-08-15
影响因子:
6.4
通讯作者:
Schuz, J.
中科院分区:
文献类型:
--
作者:
Licht, S. de Fine;Schmidt, L. S.;Schuz, J.
Little is known about the etiology of hepatoblastoma. Because of the young age at diagnosis, several studies have looked at various birth characteristics. The purpose of our study was to investigate the incidence of hepatoblastoma in the Nordic countries and the association between selected birth characteristics and hepatoblastoma. Data from national cancer registries and birth registries in Denmark, Sweden, Norway and Finland 19852006 was used. Overall, 155 children with hepatoblastoma aged 014 years were included and individually matched to five controls drawn randomly from national population registries. The incidence rate of hepatoblastoma was 1.7 per million person-years with a predominance of boys (1.5:1). Incidence rate was highest before the age of 1 year (8.3 per million person-years). A higher risk of hepatoblastoma was found in children with birth weight