Sequence comparison of the L2 and S10 genes of bluetongue viruses from the United States and the People's Republic of China

Sequence comparison of the L2 and S10 genes of bluetongue viruses from the United States and the People's Republic of China
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DOI:
10.1016/s0168-1702(99)00034-9
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发表时间:
1999-06-01
期刊:
影响因子:
5
通讯作者:
MacLachlan, NJ
MacLachlan, NJ
中科院分区:
医学3区
文献类型:
--
作者:
Bonneau, KR;Zhang, NZ;MacLachlan, NJ

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反刍动物的蓝舌病病毒(BTV)感染在美国和中国大部分地区是地方性的。对我国BTV血清型1、2、3、4、12、15和16的原型株S10和部分L2基因片段进行了测序,并与美国BTV原型株和野毒株的相同基因进行了比较。系统发育分析的S10基因分离的中国病毒成一个单系组不同的美国病毒,而类似的分析的L2基因分离株BTV根据血清型,无论地理来源。(C)1999 Elsevier Science B.V.保留所有权利。
Bluetongue virus (BTV) infection of ruminants is endemic throughout much of the US and China. The S10 and a portion of the L2 gene segments of Chinese prototype strains of BTV serotypes 1, 2, 3, 4, 12, 15, and 16 were sequenced and compared to the same genes of prototype and field strains of BTV from the US. Phylogenetic analysis of the S10 gene segregated the Chinese viruses into a monophyletic group distinct from the US viruses, whereas similar analysis of the L2 gene segregated strains of BTV according to serotype, regardless of geographic origin. (C) 1999 Elsevier Science B.V. All rights reserved.