Mechanisms of cardiac conduction: a history of revisions.
Mechanisms of cardiac conduction: a history of revisions.
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DOI：
10.1152/ajpheart.00760.2013
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发表时间：
2014-03
期刊：
影响因子：
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通讯作者：
R. Veeraraghavan;R. Gourdie;S. Poelzing
中科院分区：
文献类型：
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作者：
R. Veeraraghavan;R. Gourdie;S. Poelzing
心脏传导是电兴奋通过心脏传播的过程，触发单个肌细胞同步收缩。传导缺陷破坏同步激活，并与许多病理学中危及生命的心律失常相关。因此，毫不奇怪，这一现象继续成为积极的科学研究的主题。在这里，我们提供了一个简短的回顾，在过去的世纪的概念理解的传导已经演变，并强调最近，潜在的范式转变的发展。
Cardiac conduction is the process by which electrical excitation spreads through the heart, triggering individual myocytes to contract in synchrony. Defects in conduction disrupt synchronous activation and are associated with life-threatening arrhythmias in many pathologies. Therefore, it is scarcely surprising that this phenomenon continues to be the subject of active scientific inquiry. Here we provide a brief review of how the conceptual understanding of conduction has evolved over the last century and highlight recent, potentially paradigm-shifting developments.