SERUM SELENIUM AND CORONARY HEART-DISEASE RISK-FACTORS IN SOUTHERN ITALIAN MEN
SERUM SELENIUM AND CORONARY HEART-DISEASE RISK-FACTORS IN SOUTHERN ITALIAN MEN
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DOI：
10.1016/0021-9150(91)90015-u
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发表时间：
1991-04-01
期刊：
影响因子：
5.3
通讯作者：
MANCINI, M
中科院分区：
文献类型：
--
作者：
JOSSA, F;TREVISAN, M;MANCINI, M
在参加好利获得心脏研究的 364 名来自意大利南部的男性中，研究了血清硒浓度与许多冠心病危险因素之间的关联。 硒与血清胆固醇呈显着正相关（r = 0.120；P = 0.022），并且在调整年龄和体重指数后，这种正相关仍然存在。 重度吸烟者的硒水平低于轻度吸烟者和当前不吸烟者，但这些差异并未达到统计学显着性。 硒与任何其他冠心病危险因素（例如甘油三酯、高密度脂蛋白胆固醇、血压、年龄和体重指数）均没有显着相关性。 据推测，本研究和之前的研究报告的硒与血清胆固醇之间的关联可能是由于硒摄入量与影响血清胆固醇浓度的食物之间的饮食相互关系所致。
The association between serum selenium concentration and a number of coronary heart disease risk factors is studied in 364 males from southern Italy participating in the Olivetti Heart Study. Selenium correlates positively and significantly with serum cholesterol (r = 0.120; P = 0.022), and this positive association persists after adjustment for age and body mass index. Selenium levels in heavy smokers are lower than both light smokers and current non-smokers, but these differences do not reach statistical significance. Selenium is not significantly associated with any of the other CHD risk factors (e.g., triglycerides, HDL cholesterol, blood pressure, age, and body mass index). It is hypothesized that the association between selenium and serum cholesterol reported in this and previous studies could be due to dietary interrelationships between selenium intake and foods that affect serum cholesterol concentrations.