Drainage Retinotomy Confers Risk of Epiretinal Membrane Formation After Vitrectomy for Rhegmatogenous Retinal Detachment Repair
Drainage Retinotomy Confers Risk of Epiretinal Membrane Formation After Vitrectomy for Rhegmatogenous Retinal Detachment Repair
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DOI：
10.1016/j.ajo.2021.07.028
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发表时间：
2021-11-12
影响因子：
4.2
通讯作者：
Sonoda, Koh-hei
中科院分区：
文献类型：
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作者：
Ishikawa, Keijiro;Akiyama, Masato;Sonoda, Koh-hei
目的：描述平坦部玻璃体切割术(PPV)治疗孔源性视网膜脱离(RRD)后视网膜前膜(ERM)形成的相关因素。设计：基于注册资料的全国性、多中心临床队列研究。方法：回顾分析2016年2月至2017年3月日本视网膜脱离登记处登记的2239例应用PPV修复RRD的病例。用单因素分析评估13个基线特征和8个手术方式与ERM形成的关系。我们对显著相关的临床因素(S)进行了倾向分数匹配分析。结果：104例(4.6%)玻璃体切除术后6个月有ERM形成。我们发现，经多重检验校正后，视网膜切开引流术与ERM显著相关(优势比[OR]2.22[95%可信区间(CI)1.50-3.31]；P<；.001)。在倾向性评分匹配分析(n=492)中，我们证实了玻璃体切割术后6个月ERM的发生率有显著差异(分别为8.3%和2.6%；OR3.35[95%CI 1.77~6.33]；P<；.001)。结论：PPV联合视网膜切开术更容易发生ERM。2021；234：20-27。(C)2021 Elsevier Inc.保留所有权利。)
PURPOSE: To describe the factors associated with epiretinal membrane (ERM) formation in eyes treated with pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD).DESIGN: Nationwide, multicenter, clinical cohort study based on registry data.METHODS: We reviewed 2239 cases treated with PPV for RRD repair registered in the Japan-Retinal Detachment Registry between February 2016 and March 2017. Associations of 13 baseline characteristics and 8 surgical procedures with ERM formation were evaluated using univariate analysis. We conducted a propensity score matched analysis for the significantly associated clinical factor(s). The primary outcome measure was ERM formation after 6 months of vitrectomy.RESULTS: ERM had developed in 104 cases (4.6%) by 6 months. We found that drainage retinotomy was significantly associated with ERM after multiple testing correction (odds ratio [OR] 2.22 [95% confidence interval {CI} 1.50-3.31]; P < .001). In the propensity score-matched analysis (n = 492 in each group), we confirmed a significant difference in the incidence of ERM after 6 months of vitrectomy (8.3% and 2.6% in cases with and without drainage retinotomy, respectively; OR 3.35 [95% CI 1.77-6.33]; P < .001).CONCLUSIONS: Eyes treated with PPV combined with drainage retinotomy are more likely to develop ERM postoperatively. (Am J Ophthalmol 2021;234: 20-27. (C) 2021 Elsevier Inc. All rights reserved.)