Parity and All-cause Mortality in Women and Men: A Dose-Response Meta-Analysis of Cohort Studies.

Parity and All-cause Mortality in Women and Men: A Dose-Response Meta-Analysis of Cohort Studies.
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女性和男性的均等率和全因死亡率:队列研究的剂量反应荟萃分析

DOI:
10.1038/srep19351
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发表时间:
2016-01-13
期刊:
影响因子:
4.6
通讯作者:
Wang Q
Wang Q
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Zeng Y;Ni ZM;Liu SY;Gu X;Huang Q;Liu JA;Wang Q

文献摘要

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To quantitatively assess the association between parity and all-cause mortality, we conducted a meta-analysis of cohort studies. Relevant reports were identified from PubMed and Embase databases. Cohort studies with relative risks (RRs) and 95% confidence intervals (CIs) of all-cause mortality in three or more categories of parity were eligible. Eighteen articles with 2,813,418 participants were included. Results showed that participants with no live birth had higher risk of all-cause mortality (RR= 1.19, 95% CI = 1.03–1.38;I2= 96.7%,P< 0.001) compared with participants with one or more live births. Nonlinear dose-response association was found between parity and all-cause mortality (Pfor non-linearity < 0.0001). Our findings suggest that moderate-level parity is inversely associated with all-cause mortality.