Clinical evaluation of nerve fiber layer atrophy as an indicator of glaucomatous optic nerve damage.
Clinical evaluation of nerve fiber layer atrophy as an indicator of glaucomatous optic nerve damage.
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神经纤维层萎缩作为青光眼视神经损伤指标的临床评价。
DOI：
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发表时间：
1980
期刊：
影响因子：
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通讯作者：
T. George
中科院分区：
文献类型：
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作者：
H. Quigley;N. Miller;T. George
为了评价视网膜神经纤维层（NFL）的外观在估计青光眼视神经损害中的有用性，我们检查了335只正常眼，怀疑青光眼，青光眼患者。在视野丧失的眼中，84%的人有NFL萎缩。在正常眼中，NFL萎缩被怀疑在3%。在青光眼嫌疑人中，13%的眼睛有NFL缺陷。与视野丧失的眼睛中发现的弥漫性萎缩相比，怀疑青光眼的眼睛中的缺陷更经常是局部的。NFL异常在与视野缺损位置相对应的视网膜区域中以高精度被观察到。NFL检查在检测视野丧失的眼睛时与视盘配置一样敏感，并且可以帮助识别哪些眼睛在视野丧失之前遭受视神经损伤。
To evaluate the usefulness of the retinal nerve fiber layer (NFL) appearance in the estimation of glaucomatous optic nerve damage, we examined 335 eyes of normal, glaucoma suspect, of glaucomatous patients. In eyes with field loss, 84% had NFL atrophy. In normal eyes, NFL atrophy was suspected in 3%. In glaucoma suspects, 13% of eyes had NFL defects. Defects in glaucoma suspect eyes were more often localized, compared with the diffuse atrophy found in eyes with visual field loss. The NFL abnormalities were seen in areas of the retina corresponding to the location of visual field defects with a high accuracy. The NFL examination is as sensitive in detecting eyes with field loss as the optic disc configuration and may help to identify which eyes are suffering optic nerve damage prior to field loss.