NEAR-INFRARED SPECTROSCOPY IN PERIPHERAL VASCULAR-DISEASE
NEAR-INFRARED SPECTROSCOPY IN PERIPHERAL VASCULAR-DISEASE
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DOI：
10.1002/bjs.1800780408
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发表时间：
1991-04-01
影响因子：
9.6
通讯作者：
SCURR, JH
中科院分区：
文献类型：
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作者：
CHEATLE, TR;POTTER, LA;SCURR, JH
本文对38例受试者、21例无血管疾病的正常人和17例周围血管疾病患者的小腿肌肉进行了近红外光谱分析。 通过计算止血带诱导缺血期间氧合血红蛋白向脱氧血红蛋白的转化率，测量小牛的耗氧量。 还测量了缺血后再氧合。 外周血管疾病患者的中位耗氧量为0.10 ml/100 g组织-1 min-1，而对照组为0.20 ml/100 g组织-1 min-1（P < 0.03，Mann-Whitney U检验）。 缺血后氧合血红蛋白达到最大值的中位时间外周血管疾病患者为40 s，对照组为20 s（P < 0.02）。 结果表明，氧消耗减少周围血管疾病。 近红外光谱是一种非侵入性的方法，用于评估手术或药物治疗引起的代谢改善。
Near-infrared spectroscopy has been performed on the calf muscles of 38 subjects, 21 normal controls without vascular disease and 17 patients with peripheral vascular disease. Oxygen consumption was measured in the calf by calculating the rate of conversion of oxyhaemoglobin to deoxyhaemoglobin during a period of tourniquet-induced ischaemia. Postischaemic reoxygenation was also measured. Median oxygen consumption in patients with peripheral vascular disease was 0.10 ml 100 g tissue-1 min-1, while in the control group it was 0.20 ml 100 g tissue-1 min-1 (P < 0.03, Mann-Whitney U test). The median time taken to reach maximum oxyhaemoglobin levels after ischaemia was 40 s in patients with peripheral vascular disease and 20 s in controls (P < 0.02). The results indicate that oxygen consumption is reduced in peripheral vascular disease. Near infrared spectroscopy is a non-invasive method for assessing metabolic improvement resulting from surgical or pharmacological treatment.