Muscle development in large and small pig fetuses.
Muscle development in large and small pig fetuses.
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发表时间：
1983-09
影响因子：
2.4
通讯作者：
P. Wigmore;N. Stickland
中科院分区：
文献类型：
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作者：
P. Wigmore;N. Stickland
从妊娠38天至产后1天的窝仔中按体重选择最大和最小的窝仔。完整的半腱肌冷冻切片用于提供第一代和第二代肌纤维发育的定性和定量说明。结果表明，大窝和小窝的初级和次级纤维的形成时间以及初级纤维的形成数量是相同的。然而，在较小的胎儿中形成的次级纤维数量较少，导致出生时总纤维数量相差17%。由于中心肌原纤维无区较小，小胎的原纤维较小。这种小尺寸可能限制了二次纤维形成的可用表面积。纤维增生在妊娠85至95天停止，因此纤维数量的差异很可能是永久性的。
The largest and smallest littermates were chosen by weight from litters of 38 days' gestation to 1 day post partum. Complete frozen sections of the semitendinosus muscle were used to provide a qualitative and quantitative account of the development of the primary and secondary generations of muscle fibres. The results showed that the time of formation of primary and secondary fibres, and the numbers of primary fibres formed, were the same in both large and small littermates. The number of secondary fibres formed, however, was lower in the smaller fetuses and resulted in there being a 17% difference in total fibre number at birth. Primary fibres in small fetuses were smaller, due to the smaller central myofibril-free region. This small size may have restricted the available surface area for secondary fibre formation. Fibre hyperplasia was found to cease between 85 and 95 days' gestation, and so the fibre number difference is likely to be permanent.