PROGNOSTIC IMPLICATIONS OF NORMAL EXERCISE TOMOGRAPHIC THALLIUM IMAGES IN PATIENTS WITH ANGIOGRAPHIC EVIDENCE OF SIGNIFICANT CORONARY-ARTERY DISEASE
PROGNOSTIC IMPLICATIONS OF NORMAL EXERCISE TOMOGRAPHIC THALLIUM IMAGES IN PATIENTS WITH ANGIOGRAPHIC EVIDENCE OF SIGNIFICANT CORONARY-ARTERY DISEASE
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DOI：
10.1016/0002-9149(94)90431-6
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发表时间：
1994-10-15
影响因子：
2.8
通讯作者：
ISKANDRIAN, AS
中科院分区：
文献类型：
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作者：
FATTAH, AA;KAMAL, AM;ISKANDRIAN, AS
本研究探讨了正常运动断层铊影像对经药物治疗的冠状动脉疾病（CAD）血管造影证据患者的预后影响。有97例患者年龄为60 ± 10岁; 52例为1-、30例为2-、15例为3支血管CAD（直径狭窄≥ 50%）。51例患者（53%）的运动试验为次极量; 20例患者（21%）在运动期间发生ST段压低，23例患者（24%）在运动期间发生心绞痛。大多数患者（71%）正在接受抗心绞痛治疗。在平均32个月的随访中，仅3例患者发生心脏事件：2例死于心脏原因，1例发生非致死性心肌梗死（事件发生率1.1%/年）。这3例患者在运动时均未出现ST段阳性反应。因此，接受药物治疗的CAD患者（包括多支血管CAD患者）在正常运动铊图像的情况下具有良性预后。这些结果对患者管理和医疗服务成本具有重要意义。
This study examines the prognostic implications of normal exercise tomographic thallium images in medically treated patients with angiographic evidence of coronary artery disease (CAD). There were 97 patients aged 60 +/- 10 years; 52 had 1-, 30 had 2-, and 15 had 3-vessel CAD (greater than or equal to 50% diameter stenosis). The exercise test was submaximal in 51 patients (53%); ST-segment depression during exercise occurred in 20 patients (21%), and angina during exercise occurred in 23 patients (24%). Most patients (71%) were receiving antianginal therapy. During a mean follow-up of 32 months, only 3 patients had cardiac events: 2 died of cardiac causes and 1 had nonfatal myocardial infarction (event rate 1.1%/year). None of those 3 patients had positive ST response during exercise. Thus, medically treated patients with CAD (including those with multivessel CAD) have a benign prognosis in the presence of nor mal exercise thallium images. These results have important implications in patient management and cost of health delivery.