Carbonate Apatite Formation during the Setting Reaction of Apatite Cement
Carbonate Apatite Formation during the Setting Reaction of Apatite Cement
复制标题
磷灰石水泥凝固反应过程中碳酸盐磷灰石的形成
DOI：
10.1002/9781118217504.ch2
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
K. Ishikawa
中科院分区：
文献类型：
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作者：
Arief Cahyanto;K. Tsuru;K. Ishikawa
磷灰石骨水泥（AC）替代骨仍然是有争议的问题。为了了解可能影响 AC 替代骨骼的因素，由磷酸四钙 (TTCP; Ca4(PO4)2O) 和无水磷酸二钙 (DCPA; CaHPO4) 的等摩尔混合物组成的 AC 被允许在 5% CO2 或 N2 下在 37°C 和 100% 相对湿度下设定。当 AC 在 5% CO2 下凝固时，形成碳酸盐磷灰石 (CO3Ap)。随着离地表深度的增加，CO3 的含量逐渐减少。 CO3Ap是B型CO3Ap，其中CO3 2- 被PO4 3- 取代，并且CO3Ap存在于骨中。当AC在N 2 下凝固时，较大量的TTCP保持未反应，而当AC在CO 2 下凝固时，较小量的TTCP保持未反应。这可能是由于CO3Ap 的Ca/P 摩尔比较大造成的。 CO3Ap 和/或小的未反应 TTCP 的形成被认为是将 AC 替换为骨的关键因素。
Replacement of apatite cement (AC) to bone is still controversial issue. To understand factor that could affect the replacement of AC to bone, AC consisting of an equimolar mixture of tetracalcium phosphate (TTCP; Ca4(PO4)2O) and dicalcium phosphate anhydrous (DCPA; CaHPO4) was allowed to set at 37C and 100% relative humidity under 5% CO2 or N2. Carbonate apatite (CO3Ap) was formed when AC was allowed to set under 5% CO2. The amount of CO3 decreased gradually as the depth from the surface increased. The CO3Ap was the B-type CO3Ap in which CO3 2- was replaced with PO4 3- and the CO3Ap found in bone. Larger amount of TTCP remain unreacted when the AC was allowed to set under N2 whereas smaller amount of TTCP remain unreacted when the AC was allowed to set under CO2. This may be caused by the larger Ca/P molar ratio of CO3Ap. Formation of CO3Ap and/or small unreacted TTCP are thought to be key factors for the replacement of AC to bone.