Concept, implementations and applications of Fourier ptychography

Concept, implementations and applications of Fourier ptychography
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DOI:
10.1038/s42254-021-00280-y
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发表时间:
2021-02
影响因子:
38.5
通讯作者:
G. Zheng;Cheng Shen;Shaowei Jiang;Pengming Song;Changhuei Yang
G. Zheng;Cheng Shen;Shaowei Jiang;Pengming Song;Changhuei Yang
中科院分区:
物理与天体物理1区
文献类型:
--
作者:
G. Zheng;Cheng Shen;Shaowei Jiang;Pengming Song;Changhuei Yang

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分辨率和成像视场之间的竞争是传统成像系统中的一个长期存在的问题-它们既可以生成细节细腻的小区域图像,也可以生成细节粗糙的大区域图像。傅里叶变换(FP)是解决成像系统中这一内在权衡的一种方法。它将高通量和高分辨率成像的挑战从改善光学物理限制的领域带到了计算领域。它还实现了光学像差的测量后计算校正。我们介绍了FP的基本概念,并将其与相关的成像模式进行了比较,然后讨论了实验实现方法,如孔径扫描FP、宏观相机扫描FP、反射模式、单次拍摄设置、X射线FP、散斑扫描方案和深度学习相关的实现。讨论了FP的各种应用,包括2D和3D的定量相位成像、数字病理学、高通量细胞术、像差计量学、远程成像和相干X射线纳米检查。为有兴趣自己实现FP的读者提供了数据集和重建代码的集合。
The competition between resolution and the imaging field of view is a long-standing problem in traditional imaging systems — they can produce either an image of a small area with fine details or an image of a large area with coarse details. Fourier ptychography (FP) is an approach for tackling this intrinsic trade-off in imaging systems. It takes the challenge of high-throughput and high-resolution imaging from the domain of improving the physical limitations of optics to the domain of computation. It also enables post-measurement computational correction of optical aberrations. We present the basic concept of FP, compare it to related imaging modalities and then discuss experimental implementations, such as aperture-scanning FP, macroscopic camera-scanning FP, reflection mode, single-shot set-up, X-ray FP, speckle-scanning scheme and deep-learning-related implementations. Various applications of FP are discussed, including quantitative phase imaging in 2D and 3D, digital pathology, high-throughput cytometry, aberration metrology, long-range imaging and coherent X-ray nanoscopy. A collection of datasets and reconstruction codes is provided for readers interested in implementing FP themselves.