Acute, sub-acute and long-term subjective consequences of 'ecstasy' (MDMA) consumption in 430 regular users
Acute, sub-acute and long-term subjective consequences of 'ecstasy' (MDMA) consumption in 430 regular users
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DOI：
10.1002/hup.529
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发表时间：
2003-10-01
影响因子：
1.7
通讯作者：
Curran, HV
中科院分区：
文献类型：
--
作者：
Verheyden, SL;Henry, JA;Curran, HV
这项研究审查了报告的心理影响的不同模式的MDMA的使用在男性和女性，以及他们是如何修改使用其他精神活性物质。一个半结构化的inter-view进行了466经常MDMA用户，探索这种药物的感知急性，亚急性和长期的主观影响。因素分析确定了MDMA急性效应的三个主要类别：（一）对心理健康的积极影响和（二）消极影响，以及（三）身体影响。在亚急性效应方面，83%的参与者报告说在服用摇头丸期间情绪低落，80%的人报告说注意力受损。影响这些效应的因素包括年龄、性别、MDMA使用程度和可卡因或安非他明的伴随使用。最常报告的长期影响包括对MDMA的耐受性（59%），注意力集中能力受损（38%），抑郁症（37%）和“对人更开放”（31%）。在什么可以说服使用者停止使用MDMA方面，他们最突出的担忧是药物对心理健康的长期影响。版权所有（C）2003约翰威利父子有限公司。
This study examined the reported psychological effects of different patterns of MDMA use in men and women, and how they are modified by use of other psychoactive substances. A semi-structured inter-view was conducted with 466 regular MDMA users, exploring the perceived acute, sub-acute and long-term subjective effects of this drug. Factor analysis established three main categories of acute effects of MDMA: (i) positive and (ii) negative effects on mental health, and (iii) physical effects. In terms of subacute effects, 83% of participants reported experiencing low mood and 80% reported impaired concentration between ecstasy-taking sessions. Factors affecting these effects included age, gender, extent of MDMA use and concomitant use of cocaine or amphetamine. The long-term effects most frequently reported included the development of tolerance to MDMA (59%), impaired ability to concentrate (38%), depression (37%) and 'feeling more open towards people' (31%). In terms of what might persuade users to stop using MDMA, their most prominent concern was the drug's long-term effects on mental health. Copyright (C) 2003 John Wiley Sons, Ltd.