Spectral changes in cortical surface potentials during motor movement
Spectral changes in cortical surface potentials during motor movement
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DOI：
10.1523/jneurosci.3886-06.2007
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发表时间：
2007-02-28
影响因子：
5.3
通讯作者：
Ojemann, Jeffrey G.
中科院分区：
文献类型：
--
作者：
Miller, Kai J.;Leuthardt, Eric C.;Ojemann, Jeffrey G.
在第一个大型研究中，我们量化了22名受试者的运动相关的皮质电图信号的变化，硬膜下电极阵列用于识别癫痫灶。在癫痫病灶切除前，患者接受了5-7 d的阵列放置监测期，在此期间，他们参加了研究。一个基于间隔的电机重复任务产生一致的和可量化的光谱变化，映射到一个Talairach标准化的模板皮层。针对每个受试者的几种不同运动模式，分别为高频带（HFB）（76-100 Hz）和低频带（LFB）（8-32 Hz）创建标测图。在LFB中，随着运动，相关电极中的功率一致地降低，而在HFB中的功率一致地增加。此外，HFB的变化比LFB的变化更集中。功率变化的部位对应于感觉运动皮层的立体定向位置和个体临床皮层电标测的结果。感觉运动表征被发现是躯体定位的，定位在立体定向空间到罗兰皮层，通常遵循经典的侏儒有限的extrarolandic表示。
In the first large study of its kind, we quantified changes in electrocorticographic signals associated with motor movement across 22 subjects with subdural electrode arrays placed for identification of seizure foci. Patients underwent a 5-7 d monitoring period with array placement, before seizure focus resection, and during this time they participated in the study. An interval-based motor-repetition task produced consistent and quantifiable spectral shifts that were mapped on a Talairach-standardized template cortex. Maps were created independently for a high-frequency band (HFB) (76-100 Hz) and a low-frequency band (LFB) (8-32 Hz) for several different movement modalities in each subject. The power in relevant electrodes consistently decreased in the LFB with movement, whereas the power in the HFB consistently increased. In addition, the HFB changes were more focal than the LFB changes. Sites of power changes corresponded to stereotactic locations in sensorimotor cortex and to the results of individual clinical electrical cortical mapping. Sensorimotor representation was found to be somatotopic, localized in stereotactic space to rolandic cortex, and typically followed the classic homunculus with limited extrarolandic representation.