DEMONSTRATION OF A DUAL A-V NODAL CONDUCTION SYSTEM IN ISOLATED RABBIT HEART

DEMONSTRATION OF A DUAL A-V NODAL CONDUCTION SYSTEM IN ISOLATED RABBIT HEART
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DOI:
10.1161/01.res.19.2.378
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发表时间:
1966-01-01
影响因子:
20.1
通讯作者:
MOE, GK
MOE, GK
中科院分区:
医学1区
文献类型:
--
作者:
MENDEZ, C;MOE, GK

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在兔心脏体外制剂中,心房和心室回声在结内的传播是通过许多穿刺点的微电极记录来追踪的。复合记录表明,该结的上部在功能和空间上可分离为2条通路([α]和[β]),它们与心房和希斯束中间的最后共同通路(FCP)通信。心房回声由心房过早刺激引起,经a路从结中部经0路返回心房;回声可以在不向心室传播过早反应的情况下发生。心室回声是由他束的过早刺激引起的,从FCP通过a通道到达心房,再通过β通道返回FCP。重复往复,在结内马戏运动的性质是常见的观察。该结果完全证实了先前基于对狗心脏的间接观察得出的结论。
The intranodal propagation of atrial and ventricular echoes in in-vitro preparations of the rabbit heart was traced from microelectrode records at many puncture sites. Composite records indicate that the upper part of the node can be functionally and spatially dissociated into 2 pathways ([alpha] and [beta], which communicate with a final common pathway (FCP) about halfway between the atrium and the His bundle. Atrial echoes, induced by premature atrial stimulation, traverse the a pathway and return to the atrium from the middle part of the node over the 0 route; echoes can occur without propagation of the premature response to the ventricle. Ventricular echoes, induced by premature stimulation of the His bundle, pass from the FCP to the atrium over the a route, and back to the FCP over the [beta] route. Repetitive reciprocation, in the nature of an intranodal circus movement was commonly observed. The results completely substantiate previous conclusions based on indirect observations in the dog heart.