Effect of gold deposition onto titanium on the adsorption of alkanethiols as the protein linker functionalizing the metal surface.
Effect of gold deposition onto titanium on the adsorption of alkanethiols as the protein linker functionalizing the metal surface.
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DOI：
10.4012/dmj.2013-182
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发表时间：
2014-01
影响因子：
2.5
通讯作者：
S. Saitoh;T. Nezu;K. Sasaki;M. Taira;H. Miura
中科院分区：
文献类型：
--
作者：
S. Saitoh;T. Nezu;K. Sasaki;M. Taira;H. Miura
提出了一种新的钛基材料生物功能化的方法，即将溅射金的钛片浸入到带有羧基末端的烷基乙醇（HS-C11-COOH）溶液中。X射线光电子能谱（XPS）分析表明，金的含量随着Au溅射时间的增加而增加，100 s后达到98 at%以上。随着Au溅射时间的延长，Ti样品中的特征元素（S、C和O）的含量增加，表明Au修饰增强了Ti表面上烷基醚分子的结合。浸泡后样品的XPS（Au-S、COO（-）和OH（-）物质）和FTIR光谱（可归属于脂肪族羧酸的峰）的定性分析也支持这一点。S和Au含量之间的强正相关性证实了Au溅射是控制Ti衬底的烷醚化处理的有效方法。
A new method to enhance the biofunctionalization of Ti materials was developed by the immersion of Au-sputtered titanium plates into a solution of alkanethiol with a carboxy group end (HS-C11-COOH). X-ray photoelectron spectroscopy (XPS) analysis showed that the gold content increased with the Au sputtering time and reached over 98 at% after 100 s. The content of the characteristic alkanethiol elements (S, C, and O) in the immersed Ti specimens increased with the Au sputtering time, which indicates that the binding of alkanethiol molecules is enhanced by the Au modification on the Ti surface. Qualitative analysis of XPS (Au-S, COO(-), and OH(-) species) and FTIR spectra (peaks assignable to an aliphatic carboxylic acid) for the sample after immersion also supported this. A strong positive correlation between the S and Au content confirms that Au sputtering is an effective method to control the alkanethiol treatment of Ti substrates.