JUVENILE DIABETES-MELLITUS, OPTIC ATROPHY, SENSORY NERVE DEAFNESS, AND DIABETES-INSIPIDUS - SYNDROME
JUVENILE DIABETES-MELLITUS, OPTIC ATROPHY, SENSORY NERVE DEAFNESS, AND DIABETES-INSIPIDUS - SYNDROME
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DOI：
10.1016/s0022-3476(76)80387-3
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发表时间：
1976-01-01
影响因子：
5.1
通讯作者：
BELMONTE, MM
中科院分区：
文献类型：
--
作者：
GUNN, T;BORTOLUSSI, R;BELMONTE, MM
本文报告4例糖尿病、视神经萎缩和高频感觉神经性听力损失患者，其中2例同时伴有尿崩症。在青少年糖尿病患者中，这种综合征的发生率似乎在1/48-1/175之间。由于残疾的进行性和常染色体隐性遗传方式，需要对所有青少年糖尿病患者进行仔细监测，以了解该综合征的其他体征。
Four patients with diabetes mellitus, optic atrophy and high-frequency neurosensory hearing loss, 2 of whom also had diabetes insipidus, are described. The frequency of this syndrome among patients with juvenile diabetes appears to be between 1/48-1/175. Because of the progressive nature of the disabilities and the autosomal recessive mode of inheritance, careful monitoring of all juvenile diabetic patients for other signs of the syndrome is warranted.