CpGProD: identifying CpG islands associated with transcription start sites in large genomic mammalian sequences
CpGProD: identifying CpG islands associated with transcription start sites in large genomic mammalian sequences
复制标题
DOI：
10.1093/bioinformatics/18.4.631
复制
发表时间：
2002-04-01
期刊：
影响因子：
5.8
通讯作者：
Mouchiroud, D
中科院分区：
文献类型：
--
作者：
Ponger, L;Mouchiroud, D
结果：CpGProD 是一款用于识别大型基因组序列中与 CpG 岛相关的哺乳动物启动子区域的应用程序。尽管它严格专用于对应的特定启动子类；大约 50% 的基因，CpGProD 比其他用于启动子预测的工具表现出更高的灵敏度和特异性。值得注意的是，CpGProD 根据研究的物种（人类、小鼠）使用不同的参数。此外，CpGProD 可以预测 DNA 链上的启动子方向。可用性：http:pbil.univ-lyon1.fr/software/cpgprod.html补充信息：http://pbil.univ-lyonl.fr/software/cpgprod.html联系方式：ponger@biomserv.univ-lyon1.fr。
Results: CpGProD is an application for identifying mammalian promoter regions associated with CpG islands in large genomic sequences. Although it is strictly dedicated to this particular promoter class corresponding to; approximate to50% of the genes, CpGProD exhibits a higher sensitivity and specificity than other tools used for promoter prediction. Notably, CpGProD uses different parameters according to species (human, mouse) studied. Moreover, CpGProD predicts the promoter orientation on the DNA strand.Availability: http:pbil.univ-lyon1.fr/software/cpgprod.htmlSupplementary information: http://pbil.univ-lyonl.fr/software/cpgprod.htmlContact: ponger@biomserv.univ-lyon1.fr.