The biodistribution and pharmacokinetics of meta-iodobenzylguanidine in childhood neuroblastoma
The biodistribution and pharmacokinetics of meta-iodobenzylguanidine in childhood neuroblastoma
复制标题
间碘苄胍在儿童神经母细胞瘤中的生物分布和药代动力学
DOI:
10.1007/bf02574771
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发表时间:
2007
期刊:
影响因子:
--
通讯作者:
J. Kemshead
中科院分区:
文献类型:
--
作者:
L. Lashford;J. Moyes;R. Ott;S. Fielding;J. Babich;S. Mellors;I. Gordon;K. Evans;J. Kemshead
MIBG is generating considerable interest for the treatment of neuroblastoma. This study has investigated the biological variation in handling of the compound in children with neuroblastoma. The biodistribution of the compound has been characterised in children undergoing tracer administrations of123I and131I-mIBG. Estimates of hepatic and whole body radiation dose delivery have been made. The results indicate substantial interpatient variation in hepatic dose delivery. This organ may be critical in some patients undergoing targeted radiotherapy with mIBG.
DOI:
--
发表时间:
1984
期刊:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子:
--
作者:
Sisson,JC;Shapiro,B;Beierwaltes,WH;Glowniak,JV;Nakajo,M;Mangner,TJ;Carey,JE;Swanson,DP;Copp,JE;Satterlee,WG
通讯作者:
Satterlee,WG
DOI:
10.3322/canjclin.34.2.86
发表时间:
1984
期刊:
CA: a cancer journal for clinicians
影响因子:
--
作者:
Sisson,JC;Shapiro,B;Beierwaltes,WH;Copp,JE
通讯作者:
Copp,JE